April 20, 2009October 13, 2011 Laughter reduces inflammation by Inflammation Factor Researchers found that regular sessions of “mirthful” laughter substantially reduced inflammation markers and improved several other health indicators, such as stress hormones and cholesterol profile in Type 2 diabetics. This substantiates the theory that stress exacerbates systemic inflammation and suggests that this may be a mechanism by which chronic stress leads to disease. Read more about this study