Canola oil and tocotrienols both significantly reduce inflammation

Daily supplementation with pure canola oil or canola oil enriched with 200 mg mixed tocotrienols significantly decreased inflammation markers (CRP) by 40 to 44% in individuals with Type 2 diabetes, with the larger decrease in the enriched group. Although the pure canola oil was intended to serve as a placebo, canola oil contains a substantial amount of vitamin E and omega-3 fats, making this more of a two-arm intervention than a placebo-controlled trial. However, both interventions were quite effective. View abstract.

Ginger reduces inflammation and improves glycemic control in Type 2 diabetics

Patients with Type 2 diabetes were given 1600 mg of powdered ginger or a placebo supplement daily for 12 weeks. At the end of the trial, those taking ginger had significant reductions in C-reactive protein and PGE2 (two markers of inflammation). There were also positive changes in other markers, including fasting blood glucose, insulin, and triglycerides.  The dosage used in the trial is equivalent to about 3/4 teaspoon of ground ginger.  Read the abstract.

Avocado protects against inflammatory effect of burger–as predicted by IF Rating

Markers of inflammation increased after subjects consumed a hamburger but not when subjects  consumed avocado along with the hamburger–despite the additional fat and calories that the avocado added to a meal.  View the study abstract. 

COMMENT: This finding supports the validity of the IF Rating system as a tool for estimating inflammatory effects of mixed meals. The IF Rating of the burger is approximately -20. The IF Rating of the burger plus the avocado is approximately +97.

Coconut oil increases expression of proinflammatory genes

Researchers tested the acute effects of two meals on various markers of inflammation. One meal was rich in monounsaturated fatty acids from macademia nut oil while the other was rich in medium chain saturated fats from coconut oil. Although there were no significant differences between the effects of the two meals on CRP (which was unchanged) or IL-6 (which increased), the coconut oil-rich meal led to significant changes in the expression of pro-inflammatory genes. The researchers conclude that “Medium-chain SFA seems more proinflammatory than MUFA, judged by the gene expression in muscle and adipose tissue of [subjects].” View the entire paper here.