In a small pilot study, researchers from University of Sao Paolo, Brazil, tested the effects of three meals on blood markers of inflammation. The three meals were similar in calories, fats, carbohydrates, and protein. However, one had a positive IF Rating, one had a negative IF Rating, and one was neutral. The IF Rating of the meal accurately predicted inflammatory response, as measured by changes in IL-6, IL-10, and TNF-a. A larger study is in the planning stages.